Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism

Despite improved clinical outcomes of diffuse large B-cell lymphoma, a certain proportion of patients still develop a primary refractory disease. To overcome these lymphomas that are intractable to existing treatment strategies, the tumor microenvironment has been identified as a potential therapeut...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Aoki, Tomohiro, Shimada, Kazuyuki, Sakamoto, Akihiko, Sugimoto, Keiki, Morishita, Takanobu, Kojima, Yuki, Shimada, Satoko, Kato, Seiichi, Iriyama, Chisako, Kuno, Shunsuke, Harada, Yasuhiko, Tomita, Akihiro, Hayakawa, Fumihiko, Kiyoi, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355079/
https://ncbi.nlm.nih.gov/pubmed/28055963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14393
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