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Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
Cell lines have been used for drug discovery as useful models of cancers; however, they do not recapitulate cancers faithfully, especially in the points of rapid growth rate and microenvironment independency. Consequently, the majority of conventional anti-cancer drugs are less sensitive to slow gro...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538400/ https://ncbi.nlm.nih.gov/pubmed/26278963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13054 |
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