The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia

Acute myeloid leukemia (AML) is a highly heterogeneous disease and internal tandem duplication mutation in FMS-like tyrosine-kinase-3 (FLT3-ITD) has a negative impact on outcome. Finding effective treatment regimens is desperately needed. In this study, we explored the inhibitory effect and mechanis...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Xia, Yin, Xiufeng, Wang, Huafeng, Huang, Jiansong, Yu, Mengxia, Ma, Zhixin, Li, Chenying, Zhou, Yile, Yan, Xiao, Huang, ShuJuan, Jin, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355052/
https://ncbi.nlm.nih.gov/pubmed/28061447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14463
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