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Bone pain induced by multiple myeloma is reduced by targeting V-ATPase and ASIC3

Multiple myeloma (MM) patients experience severe bone pain (MMBP) that is undertreated and poorly understood. In this study, we studied MMBP in an intratibial mouse xenograft model which employs JJN3 human MM cells. In this model, mice develop MMBP associated in bone with increased sprouting of calc...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Hiasa, Masahiro, Okui, Tatsuo, Allette, Yohance M, Ripsch, Matthew S, Sun-Wada, Ge-Hong, Wakabayashi, Hiroki, Roodman, G David, White, Fletcher A., Yoneda, Toshiyuki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355000/
https://ncbi.nlm.nih.gov/pubmed/28254863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3545
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