Bone marrow adipocytes facilitate fatty acid oxidation activating AMPK and a transcriptional network supporting survival of acute monocytic leukemia cells

Leukemia cells in the bone marrow (BM) must meet the biochemical demands of increased cell proliferation and also survive by continually adapting to fluctuations in nutrient and oxygen availability. Thus, targeting metabolic abnormalities in leukemia cells located in the BM is a novel therapeutic ap...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Tabe, Yoko, Yamamoto, Shinichi, Saitoh, Kaori, Sekihara, Kazumasa, Monma, Norikazu, Ikeo, Kazuho, Mogushi, Kaoru, Shikami, Masato, Ruvolo, Vivian, Ishizawa, Jo, Hail, Numsen, Kazuno, Saiko, Igarashi, Mamoru, Matsushita, Hiromichi, Yamanaka, Yasunari, Arai, Hajime, Nagaoka, Isao, Miida, Takashi, Hayashizaki, Yoshihide, Konopleva, Marina, Andreeff, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354955/
https://ncbi.nlm.nih.gov/pubmed/28108519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1645
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak