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Sprouty2 correlates with favorable prognosis of gastric adenocarcinoma via suppressing FGFR2-induced ERK phosphorylation and cancer progression

Fibroblast growth factor receptor 2 (FGFR2) has been identified as a predictive biomarker for unfavorable prognosis of gastric adenocarcinoma. As a well-defined antagonist in FGFR2-induced RAS/ERK activation, ectopic expression of sprouty (SPRY) family was reported in several kinds of cancers except...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Xu, Yunfei, Yang, Xiaoqing, Li, Zhen, Li, Shuo, Guo, Sen, Ismail, Sayed, Liu, Hongda, Huang, Zhihong, Zhang, Zongli, Chen, Yuxin, Sun, Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354878/
https://ncbi.nlm.nih.gov/pubmed/28002800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13982
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