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Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase

Tumor therapy needs new approaches in order to improve efficacy and reduce toxicity of the current treatments. The acidic microenvironment and the expression of high levels of endogenous non-telomerase reverse transcriptase (RT) are common features of malignant tumor cells. The anti-acidic proton pu...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Lugini, Luana, Sciamanna, Ilaria, Federici, Cristina, Iessi, Elisabetta, Spugnini, Enrico Pierluigi, Fais, Stefano
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354819/
https://ncbi.nlm.nih.gov/pubmed/27926505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13792
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