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Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy

The vacuolar ATPases are ATP-dependent proton pumps whose functions include the acidification of intracellular compartments and the extrusion of protons through the cell cytoplasmic membrane. These pumps play a pivotal role in the regulation of cell pH in normal cells and, to a much greater extent,...

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Detalhes bibliográficos
Main Authors: Spugnini, Enrico P, Citro, Gennaro, Fais, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876100/
https://ncbi.nlm.nih.gov/pubmed/20459683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-44
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