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Melatonin protects against arsenic trioxide-induced liver injury by the upregulation of Nrf2 expression through the activation of PI3K/AKT pathway
Melatonin has been demonstrated to have anti-inflammatory and antioxidant effects. The aim of this study was to investigate the protective effects of melatonin on arsenic trioxide (As(2)O(3))-induced toxicity in liver and oxidative stress in rats. The rats were injected with 3mg/kg As(2)O(3) on alte...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354794/ https://ncbi.nlm.nih.gov/pubmed/27980225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13931 |
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