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Melatonin ameliorates ANIT-induced cholestasis by activating Nrf2 through a PI3K/Akt-dependent pathway in rats

Cholestasis is a devastating liver condition which is increasing in prevalence worldwide; however, its underlying pathogenic mechanisms remain to be fully elucidated. It was hypothesised that melatonin may alleviate the hepatic injury associated with cholestasis due to its established antioxidant ef...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Li, Yunzhou, Yu, Han, Xu, Zongying, Shi, Shaohua, Wang, Dingnan, Shi, Xinghua, Wang, Yuchen, Zeng, Baihui, Deng, Huifang, Deng, Xiulan, Zhong, Xianggen
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323259/
https://ncbi.nlm.nih.gov/pubmed/30569102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9746
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