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Targeted delivery of CRISPR/Cas9 to prostate cancer by modified gRNA using a flexible aptamer-cationic liposome

The potent ability of CRISPR/Cas9 system to inhibit the expression of targeted gene is being exploited as a new class of therapeutics for a variety of diseases. However, the efficient and safe delivery of CRISPR/Cas9 into specific cell populations is still the principal challenge in the clinical dev...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhen, Shuai, Takahashi, Yoichiro, Narita, Shunichi, Yang, Yi-Chen, Li, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354738/
https://ncbi.nlm.nih.gov/pubmed/28030843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14072
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