Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor

Corticosteroids, such as dexamethasone, are routinely used as palliative care in neuro-oncology for their anti-inflammatory benefits, however many patients experience dose limiting side effects caused by glucocorticoid response element (GRE)-mediated transcription. The purpose of this study was to u...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wells, Elizabeth, Kambhampati, Madhuri, Damsker, Jesse M, Gordish-Dressman, Heather, Yadavilli, Sridevi, Becher, Oren J, Gittens, Jamila, Stampar, Mojca, Packer, Roger J, Nazarian, Javad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354737/
https://ncbi.nlm.nih.gov/pubmed/28030841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14070
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