Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice

Anticancer therapies that induce DNA damage tend to trigger senescence in cancer cells, a process known as therapy-induced senescence (TIS). Such cells may undergo atypical divisions, thus contributing to tumor re-growth. Accumulation of senescent cancer cells reduces survival of patients after chem...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Was, Halina, Barszcz, Kamila, Czarnecka, Joanna, Kowalczyk, Agata, Bernas, Tytus, Uzarowska, Ewelina, Koza, Paulina, Klejman, Agata, Piwocka, Katarzyna, Kaminska, Bozena, Sikora, Eva
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354733/
https://ncbi.nlm.nih.gov/pubmed/28030837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14066
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