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Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice
Anticancer therapies that induce DNA damage tend to trigger senescence in cancer cells, a process known as therapy-induced senescence (TIS). Such cells may undergo atypical divisions, thus contributing to tumor re-growth. Accumulation of senescent cancer cells reduces survival of patients after chem...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354733/ https://ncbi.nlm.nih.gov/pubmed/28030837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14066 |
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