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Lysosomal adaptation: How cells respond to lysosomotropic compounds

Lysosomes are acidic organelles essential for degradation and cellular homoeostasis and recently lysosomes have been shown as signaling hub to respond to the intra and extracellular changes (e.g. amino acid availability). Compounds including pharmaceutical drugs that are basic and lipophilic will be...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Lu, Shuyan, Sung, Tae, Lin, Nianwei, Abraham, Robert T., Jessen, Bart A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354416/
https://ncbi.nlm.nih.gov/pubmed/28301521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173771
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