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Lysosomal adaptation: How cells respond to lysosomotropic compounds

Lysosomes are acidic organelles essential for degradation and cellular homoeostasis and recently lysosomes have been shown as signaling hub to respond to the intra and extracellular changes (e.g. amino acid availability). Compounds including pharmaceutical drugs that are basic and lipophilic will be...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Lu, Shuyan, Sung, Tae, Lin, Nianwei, Abraham, Robert T., Jessen, Bart A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354416/
https://ncbi.nlm.nih.gov/pubmed/28301521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173771
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