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Follistatin attenuates radiation-induced fibrosis in a murine model

PURPOSE: Fibrosis can be a disabling, severe side effect of radiotherapy that can occur in patients, and for which there is currently no effective treatment. The activins, proteins which are members of the TGFβ superfamily, have a major role in stimulating the inflammatory response and subsequent fi...

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Veröffentlicht in:PLoS One
Hauptverfasser: Forrester, Helen B., de Kretser, David M., Leong, Trevor, Hagekyriakou, Jim, Sprung, Carl N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354399/
https://ncbi.nlm.nih.gov/pubmed/28301516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173788
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