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Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats

Foetal midbrain progenitors have been shown to survive, give rise to different classes of dopamine neurons and integrate into the host brain alleviating Parkinsonian symptoms following transplantation in patients and animal models of the disease. Dopamine neuron subpopulations in the midbrain, namel...

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Détails bibliographiques
Publié dans:Exp Neurol
Auteurs principaux: Fjodorova, Marija, Torres, Eduardo M, Dunnett, Stephen B
Format: Artigo
Langue:Inglês
Publié: Academic Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354310/
https://ncbi.nlm.nih.gov/pubmed/28131726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.01.010
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