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Tools and strategies for scarless allele replacement in Drosophila using CRISPR/Cas9

Genome editing via the CRISPR/Cas9 RNA-guided nuclease system has opened up exciting possibilities for genetic analysis. However, technical challenges associated with homology-directed repair have proven to be roadblocks for producing changes in the absence of unwanted, secondary mutations commonly...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Fly (Austin)
मुख्य लेखकों: Lamb, Abigail M., Walker, Elizabeth A., Wittkopp, Patricia J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354236/
https://ncbi.nlm.nih.gov/pubmed/27494619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336934.2016.1220463
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