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A Novel Nonsense Mutation in PANK2 Gene in Two Patients with Pantothenate Kinase-Associated Neurodegeneration

Pantothenate kinase- associated neurodegeneration (PKAN) syndrome is a rare autosomal recessive disorder characterized by progressive extrapyramidal dysfunction and iron accumulation in the brain and axonal spheroids in the central nervous system. It has been shown that the disorder is caused by mut...

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Publicat a:Int J Mol Cell Med
Autors principals: Ghafouri-Fard, Soudeh, Yassaee, Vahid Reza, Rezayi, Alireza, Hashemi-Gorji, Feyzollah, Alipour, Nasrin, Miryounesi, Mohammad
Format: Artigo
Idioma:Inglês
Publicat: Babol University of Medical Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353987/
https://ncbi.nlm.nih.gov/pubmed/28357202
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