IRFinder: assessing the impact of intron retention on mammalian gene expression

Intron retention (IR) occurs when an intron is transcribed into pre-mRNA and remains in the final mRNA. We have developed a program and database called IRFinder to accurately detect IR from mRNA sequencing data. Analysis of 2573 samples showed that IR occurs in all tissues analyzed, affects over 80%...

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Опубликовано в: :Genome Biol
Главные авторы: Middleton, Robert, Gao, Dadi, Thomas, Aubin, Singh, Babita, Au, Amy, Wong, Justin J-L, Bomane, Alexandra, Cosson, Bertrand, Eyras, Eduardo, Rasko, John E. J., Ritchie, William
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
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Software
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353968/
https://ncbi.nlm.nih.gov/pubmed/28298237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1184-4
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