Secreted phospholipase A2 of Clonorchis sinensis activates hepatic stellate cells through a pathway involving JNK signalling

BACKGROUND: Secreted phospholipase A2 (sPLA2) is a protein secreted by Clonorchis sinensis and is a component of excretory and secretory products (CsESPs). Phospholipase A2 is well known for its role in liver fibrosis and inhibition of tumour cells. The JNK signalling pathway is involved in hepatic...

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Enregistré dans:
Détails bibliographiques
Publié dans:Parasit Vectors
Auteurs principaux: Wu, Yinjuan, Li, Ye, Shang, Mei, Jian, Yu, Wang, Caiqin, Bardeesi, Adham Sameer A., Li, Zhaolei, Chen, Tingjin, Zhao, Lu, Zhou, Lina, He, Ai, Huang, Yan, Lv, Zhiyue, Yu, Xinbing, Li, Xuerong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353963/
https://ncbi.nlm.nih.gov/pubmed/28302166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-2082-z
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