Secreted phospholipase A2 of Clonorchis sinensis activates hepatic stellate cells through a pathway involving JNK signalling

BACKGROUND: Secreted phospholipase A2 (sPLA2) is a protein secreted by Clonorchis sinensis and is a component of excretory and secretory products (CsESPs). Phospholipase A2 is well known for its role in liver fibrosis and inhibition of tumour cells. The JNK signalling pathway is involved in hepatic...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Wu, Yinjuan, Li, Ye, Shang, Mei, Jian, Yu, Wang, Caiqin, Bardeesi, Adham Sameer A., Li, Zhaolei, Chen, Tingjin, Zhao, Lu, Zhou, Lina, He, Ai, Huang, Yan, Lv, Zhiyue, Yu, Xinbing, Li, Xuerong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353963/
https://ncbi.nlm.nih.gov/pubmed/28302166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-2082-z
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