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HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance

The human leukocyte antigen (HLA) class II antigen-processing machinery (APM) presents to cognate CD4(+) T-cells antigenic peptides mainly generated from exogeneous proteins in the endocytic compartment. These CD4(+) T cells exert helper function, but may also act as effector cells, thereby recogniz...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Seliger, Barbara, Kloor, Matthias, Ferrone, Soldano
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353941/
https://ncbi.nlm.nih.gov/pubmed/28344859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1171447
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