The differentiation and plasticity of Tc17 cells are regulated by CTLA-4-mediated effects on STATs

As the blockade of inhibitory surface-molecules such as CTLA-4 on T cells has led to recent advances in antitumor immune therapy, there is great interest in identifying novel mechanisms of action of CD8(+) T cells to evoke effective cytotoxic antitumor responses. Using in vitro and in vivo models, w...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Arra, Aditya, Lingel, Holger, Kuropka, Benno, Pick, Jonas, Schnoeder, Tina, Fischer, Thomas, Freund, Christian, Pierau, Mandy, Brunner-Weinzierl, Monika C.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353899/
https://ncbi.nlm.nih.gov/pubmed/28344884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1273300
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