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Optimization of the Expression of DT386-BR2 Fusion Protein in Escherichia coli using Response Surface Methodology

BACKGROUND: The aim of this study was to determine the best condition for the production of DT386-BR2 fusion protein, an immunotoxin consisting of catalytic and translocation domains of diphtheria toxin fused to BR2, a cancer specific cell penetrating peptide, for targeted eradication of cancer cell...

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Detalhes bibliográficos
Publicado no:Adv Biomed Res
Main Authors: Shafiee, Fatemeh, Rabbani, Mohammad, Jahanian-Najafabadi, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353773/
https://ncbi.nlm.nih.gov/pubmed/28349025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2277-9175.201334
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