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Alkaline ceramidase 2 is a novel direct target of p53 and induces autophagy and apoptosis through ROS generation
ACER2 is a critical sphingolipid metabolizing enzyme, and has been shown to be remarkably up-regulated following various stimuli such as DNA damage. However, the transcriptional regulatory mechanism of ACER2 gene and its potential role in the regulation of autophagy remain unknown. In this study, we...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5353723/ https://ncbi.nlm.nih.gov/pubmed/28294157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44573 |
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