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Targeted disruption of luteinizing hormone β-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility

Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) act on gonadal cells to promote steroidogenesis and gametogenesis. Clarifying the in vivo roles of LH and FSH permits a feasible approach to contraception involving selective blockade of gonadotropin action. One way to address these phy...

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Detalhes bibliográficos
Main Authors: Ma, Xiaoping, Dong, Yanlan, Matzuk, Martin M., Kumar, T. Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535369/
https://ncbi.nlm.nih.gov/pubmed/15569941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404743101
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