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Application of conventional molecular dynamics simulation in evaluating the stability of apomyoglobin in urea solution

In this study, we had exploited the advancement in computer technology to determine the stability of four apomyoglobin variants namely wild type, E109A, E109G and G65A/G73A by conducting conventional molecular dynamics simulations in explicit urea solution. Variations in RMSD, native contacts and so...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Dawei, Lazim, Raudah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353640/
https://ncbi.nlm.nih.gov/pubmed/28300210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44651
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