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Catalyzed Decomposition of Urea. Molecular Dynamics Simulations of the Binding of Urea to Urease

We present the results of molecular dynamics simulations on the urea/urease system. The starting structure was prepared from the 2.0Å crystal structure of Benini et al. of DAP-inhibited urease (PDB code 3UBP),1 and the trimeric structure (2479 residues) resulted in 180K atoms after solvation by wate...

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Detalhes bibliográficos
Main Authors: Estiu, Guillermina, Merz, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505355/
https://ncbi.nlm.nih.gov/pubmed/16584179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052020p
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