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Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes

Doxorubicin is a highly effective anticancer agent but causes cardiotoxicity in many patients. The mechanisms of doxorubicin-induced cardiotoxicity remain incompletely understood. Here we investigated doxorubicin-induced cytotoxicity in human induced pluripotent stem cells-derived cardiomyocytes (iP...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Zhao, Liqun, Zhang, Baolin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353581/
https://ncbi.nlm.nih.gov/pubmed/28300219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44735
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