PD-L1 Expression by Two Complementary Diagnostic Assays and mRNA In Situ Hybridization in Small Cell Lung Cancer

INTRODUCTION: Therapeutic antibodies to immune checkpoints show promising results. Programmed death-ligand 1 (PD-L1), an immune checkpoint ligand, blocks the cancer immunity cycle by binding the PD-L1 receptor (programmed death 1). We investigated PD-L1 protein expression and messenger RNA (mRNA) le...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thorac Oncol
Prif Awduron: Yu, Hui, Batenchuk, Cory, Badzio, Andrzej, Boyle, Theresa A., Czapiewski, Piotr, Chan, Daniel C., Lu, Xian, Gao, Dexiang, Ellison, Kim, Kowalewski, Ashley A., Rivard, Christopher J., Dziadziuszko, Rafal, Zhou, Caicun, Hussein, Maen, Richards, Donald, Wilks, Sharon, Monte, Marc, Edenfield, William, Goldschmidt, Jerome, Page, Ray, Ulrich, Brian, Waterhouse, David, Close, Sandra, Jassem, Jacek, Kulig, Kimary, Hirsch, Fred R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353355/
https://ncbi.nlm.nih.gov/pubmed/27639678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.09.002
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