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ECRG2 enhances the anti-cancer effects of cisplatin in cisplatin-resistant esophageal cancer cells via upregulation of p53 and downregulation of PCNA

AIM: To explore the anti-tumor effects of esophageal cancer-related gene 2 (ECRG2) in combination with cisplatin (DDP) in DDP-resistant esophageal cancer cells (EC9706/DDP). METHODS: A drug-resistant cell model was established, with EC9706/DDP cells being treated with ECRG2 and/or DDP. Cell viabilit...

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Podrobná bibliografie
Vydáno v:World J Gastroenterol
Hlavní autoři: Hou, Xin-Fang, Xu, Lin-Ping, Song, Hai-Yan, Li, Shuai, Wu, Chen, Wang, Ju-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352920/
https://ncbi.nlm.nih.gov/pubmed/28348485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i10.1796
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