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Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma

AIM: To study the mechanisms responsible for inactivation of a novel esophageal cancer related gene 4 (ECRG4) in esophageal squamous cell carcinoma (ESCC). METHODS: A pair of primers was designed to amplify a 220 bp fragment, which contains 16 CpG sites in the core promoter region of the ECRG 4 gene...

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Bibliografische gegevens
Gepubliceerd in:World J Gastroenterol
Hoofdauteurs: Yue, Chun-Mei, Deng, Da-Jun, Bi, Mei-Xia, Guo, Li-Ping, Lu, Shih-Hsin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Baishideng Publishing Group Inc 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611778/
https://ncbi.nlm.nih.gov/pubmed/12800218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i6.1174
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