BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage

Loss-of-function mutations in gene encoding DJ-1 contribute to the pathogenesis of autosomal recessive early-onset familial forms of Parkinson's disease (PD). DJ-1 is a multifunctional protein and plays a protective role against oxidative stress-induced mitochondrial damage and cell death, but...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Qin, Li-xia, Tan, Jie-qiong, Zhang, Hai-nan, Rizwana, Kousar, Lu, Jia-hong, Tang, Jian-guang, Jiang, Bo, Shen, Xiang-min, Guo, Ji-feng, Tang, Bei-sha, Tan, Li-ming, Wang, Chun-yu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352890/
https://ncbi.nlm.nih.gov/pubmed/28348719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5094934
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