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HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature

The Hsp70/Hsp90 organising protein (HOP) is a co-chaperone essential for client protein transfer from Hsp70 to Hsp90 within the Hsp90 chaperone machine. Although HOP is upregulated in various cancers, there is limited information from in vitro studies on how HOP expression is regulated in cancer. Th...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Mattison, Stacey A, Blatch, Gregory L, Edkins, Adrienne L
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352595/
https://ncbi.nlm.nih.gov/pubmed/27987076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0755-8
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