COMPARISON OF THE SINGLE-DOSE PHARMACOKINETICS, PHARMACODYNAMICS, AND SAFETY OF TWO NOVEL ORAL FORMULATIONS OF DIMETHANDROLONE UNDECANOATE (DMAU): A POTENTIAL ORAL, MALE CONTRACEPTIVE

Dimethandrolone (DMA, 7α,11β-dimethyl-19-nortestosterone) has both androgenic and progestational activities, ideal properties for a male hormonal contraceptive. In vivo, dimethandrolone undecanoate (DMAU) is hydrolyzed to DMA. We showed previously that single oral doses of DMAU powder-in-capsule tak...

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Detalhes bibliográficos
Publicado no:Andrology
Main Authors: Ayoub, Rosana, Page, Stephanie T., Swerdloff, Ronald S., Liu, Peter Y., Amory, John K., Leung, Andrew, Hull, Laura, Blithe, Diana, Christy, Alicia, Chao, Jing H., Bremner, William J., Wang, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352517/
https://ncbi.nlm.nih.gov/pubmed/27907978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/andr.12303
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