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Dimethandrolone Undecanoate, a Novel, Nonaromatizable Androgen, Increases P1NP in Healthy Men Over 28 Days

CONTEXT: Dimethandrolone undecanoate (DMAU) is being developed as a male contraceptive. Daily oral administration of DMAU, a potent androgen that is not aromatized, markedly suppresses serum testosterone (T) and estradiol (E(2)) in healthy men. E(2) deficiency can increase bone resorption in men. OB...

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Vydáno v:J Clin Endocrinol Metab
Hlavní autoři: Thirumalai, Arthi, Yuen, Fiona, Amory, John K, Hoofnagle, Andrew N, Swerdloff, Ronald S, Liu, Peter Y, Long, Jill E, Blithe, Diana L, Wang, Christina, Page, Stephanie T
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765650/
https://ncbi.nlm.nih.gov/pubmed/33090208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa761
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