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Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders

Recent studies show that the complex genetic architecture of schizophrenia (SZ) is driven in part by polygenic components, or the cumulative effect of variants of small effect in many genes, as well as rare single-locus variants with large effect sizes. Here we discuss genetic aberrations known as c...

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Pubblicato in:J Neurosci Res
Autori principali: Rutkowski, Timothy P., Schroeder, Jason P., Gafford, Georgette M., Warren, Stephen T., Weinshenker, David, Caspary, Tamara, Mulle, Jennifer G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352473/
https://ncbi.nlm.nih.gov/pubmed/27859486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23970
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