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Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome.

We have identified and extensively characterized a type IV collagen alpha chain, referred to as alpha 5(IV). Four overlapping cDNA clones isolated contain an open reading frame for 543 amino acid residues of the carboxyl-terminal end of a collagenous domain, a 229-residue carboxyl-terminal noncollag...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hostikka, S L, Eddy, R L, Byers, M G, Höyhtyä, M, Shows, T B, Tryggvason, K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1689491/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1606
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