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Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome.

We have identified and extensively characterized a type IV collagen alpha chain, referred to as alpha 5(IV). Four overlapping cDNA clones isolated contain an open reading frame for 543 amino acid residues of the carboxyl-terminal end of a collagenous domain, a 229-residue carboxyl-terminal noncollag...

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Detalhes bibliográficos
Main Authors: Hostikka, S L, Eddy, R L, Byers, M G, Höyhtyä, M, Shows, T B, Tryggvason, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53524/
https://ncbi.nlm.nih.gov/pubmed/1689491
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