CHIR99021 combined with retinoic acid promotes the differentiation of primordial germ cells from human embryonic stem cells

Primordial germ cells (PGCs) derived from human embryonic stem cells (hESCs) represent as a desirable experimental model as well as a potential strategy for treating male infertility. Here, we developed a simple and feasible method for differentiation of PGCs from hESCs by using CHIR99021 (an inhibi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Cheng, Tingting, Zhai, Kui, Chang, Yan, Yao, Guidong, He, Jiahuan, Wang, Fang, Kong, Huijuan, Xin, Hang, Wang, Huiwen, Jin, Meng, Gong, Bing, Gu, Lei, Yang, Zhiguang, Wu, Yanyun, Ji, Guangju, Sun, Yingpu
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352363/
https://ncbi.nlm.nih.gov/pubmed/27999196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13958
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