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Genetic Bases of the Rifampin Resistance Phenotype in Brucella spp.

Rifampin is one of the most potent and broad-spectrum antibiotics against bacterial pathogens. Its bactericidal activity is due to its ability to bind to the β subunit of the DNA-dependent RNA polymerase encoded by the rpoB gene. Mutations of the rpoB gene have been characterized in rifampin-resista...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marianelli, Cinzia, Ciuchini, Franco, Tarantino, Michela, Pasquali, Paolo, Adone, Rosanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC535235/
https://ncbi.nlm.nih.gov/pubmed/15583262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.12.5439-5443.2004
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