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Genetic Bases of the Rifampin Resistance Phenotype in Brucella spp.
Rifampin is one of the most potent and broad-spectrum antibiotics against bacterial pathogens. Its bactericidal activity is due to its ability to bind to the β subunit of the DNA-dependent RNA polymerase encoded by the rpoB gene. Mutations of the rpoB gene have been characterized in rifampin-resista...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535235/ https://ncbi.nlm.nih.gov/pubmed/15583262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.12.5439-5443.2004 |
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