T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice

Nonresolving inflammation is involved in the initiation and progression process of tumorigenesis. Src homology 2 domain-containing tyrosine phosphatase 2 (SHP2) is known to inhibit acute inflammation but its role in chronic inflammation-associated cancer remains unclear. The role of SHP2 in T cells...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Wen, Guo, Wenjie, Shen, Lihong, Chen, Zhen, Luo, Qiong, Luo, Xiaolin, Feng, GenSheng, Shu, Yongqian, Gu, Yanhong, Xu, Qiang, Sun, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352345/
https://ncbi.nlm.nih.gov/pubmed/27935860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13812
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