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Patient-derived ovarian cancer xenografts re-growing after a cisplatinum treatment are less responsive to a second drug re-challenge: a new experimental setting to study response to therapy

Even if ovarian cancer patients are very responsive to a cisplatinum-based therapy, most will relapse with a resistant disease. New experimental animal models are needed to explore the mechanisms of resistance, to better tailor treatment and improve patient prognosis. To address these aims, seven pa...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ricci, Francesca, Fratelli, Maddalena, Guffanti, Federica, Porcu, Luca, Spriano, Filippo, Dell’Anna, Tiziana, Fruscio, Robert, Damia, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352333/
https://ncbi.nlm.nih.gov/pubmed/26910918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7465
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