Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

PURPOSE: Oseltamivir is widely used in the treatment and prophylaxis of influenza A and B viral infections. It is ingested as an oral prodrug that is rapidly metabolized by carboxylesterase 1 (CES1) to its active form, oseltamivir carboxylate. Dexamethasone is also used in the treatment of acute res...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Jang, Kyungho, Kim, Min-Kyoung, Oh, Jaeseong, Lee, SeungHwan, Cho, Joo-Youn, Yu, Kyung-Sang, Choi, Tai Kiu, Lee, Sang-Hyuk, Lim, Kyoung Soo
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352149/
https://ncbi.nlm.nih.gov/pubmed/28331290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S124307
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