Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism

Kaposi’s Sarcoma associated Herpesvirus (KSHV), an oncogenic, human gamma-herpesvirus, is the etiological agent of Kaposi’s Sarcoma the most common tumor of AIDS patients world-wide. KSHV is predominantly latent in the main KS tumor cell, the spindle cell, a cell of endothelial origin. KSHV modulate...

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Vydáno v:PLoS Pathog
Hlavní autoři: Sychev, Zoi E., Hu, Alex, DiMaio, Terri A., Gitter, Anthony, Camp, Nathan D., Noble, William S., Wolf-Yadlin, Alejandro, Lagunoff, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352148/
https://ncbi.nlm.nih.gov/pubmed/28257516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006256
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