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A magnesium-induced triplex pre-organizes the SAM-II riboswitch
Our (13)C- and (1)H-chemical exchange saturation transfer (CEST) experiments previously revealed a dynamic exchange between partially closed and open conformations of the SAM-II riboswitch in the absence of ligand. Here, all-atom structure-based molecular simulations, with the electrostatic effects...
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| Publicado en: | PLoS Comput Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352136/ https://ncbi.nlm.nih.gov/pubmed/28248966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005406 |
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