Magnesium Fluctuations Modulate RNA Dynamics in the SAM-I Riboswitch

Experiments demonstrate that Mg(2+) is crucial for structure and function of RNA systems, yet the detailed molecular mechanism of Mg(2+) action on RNA is not well understood. We investigate the interplay between RNA and Mg(2+) at atomic resolution through ten 2 microsecond explicit solvent molecular...

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Main Authors: Hayes, Ryan L., Noel, Jeffrey K., Mohanty, Udayan, Whitford, Paul C., Hennelly, Scott P., Onuchic, José N., Sanbonmatsu, Karissa Y.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675279/
https://ncbi.nlm.nih.gov/pubmed/22612276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301454u
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